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The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM | EMBO reports
![Left: mitochondrial transcription factor A (Tfam) is a nuclear-encoded... | Download Scientific Diagram Left: mitochondrial transcription factor A (Tfam) is a nuclear-encoded... | Download Scientific Diagram](https://www.researchgate.net/publication/300382863/figure/fig1/AS:417510835933184@1476553748328/Left-mitochondrial-transcription-factor-A-Tfam-is-a-nuclear-encoded-transcription.png)
Left: mitochondrial transcription factor A (Tfam) is a nuclear-encoded... | Download Scientific Diagram
![Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation | Nature Communications Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fncomms4077/MediaObjects/41467_2014_Article_BFncomms4077_Fig1_HTML.jpg)
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation | Nature Communications
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![Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease - ScienceDirect Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1097276512009045-fx1.jpg)
Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease - ScienceDirect
![Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors | Cell Death & Disease Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors | Cell Death & Disease](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41419-021-04255-w/MediaObjects/41419_2021_4255_Fig7_HTML.png)
Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors | Cell Death & Disease
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